Amicus Therapeutics leads in the treatment of lysosomal storage disorders.

Amicus Therapeutics Biopharmaceutical Company is located in Cranbury, New Jersey. However, in 2008 it grew into a larger firm and expanded from its original set up in Cranbury to a second research site in San Diego. The company was established by major investors including Canaan Partners, Radius Ventures, and New Enterprise Associates.The company`s therapeutical products development relies on the Chaperone Advanced Replacement Therapy (CHART) technology. It has also focused on the development of enzyme replacement therapies (ERTs).

 

Amicus Therapeutics establishes and develops drugs and medicines that treat lysosomal storage disorders, a rare disease. Unlike other types of treatments which focus on replacing defective enzymes, Amicus Therapeutics uses the small molecule pharmacological chaperones which bind to a victim`s defective proteins and help to restore their functions and activities in the body. In 2014 Amicus Therapeutics Biopharmaceutical Company had the extensive portfolio of small molecule pharmacological chaperones among all other pharmaceutical firms.

 

In 2014 they developed Migalastat, an advanced pharmacological chaperone for treating Fabry disease. The main aim of the product is to stabilize endogenous mutant alpha-galactosidase (https://seekingalpha.com/article/4073303-amicus-therapeutics-small-biotech-seems-big-mo). In 2013 Amicus Therapeutics established enzyme replacement therapy for the treatment of a rare disease known as Pombe by use of candidate AT2220. They also developed another candidate, Plicera for the treatment of Gaucher disease.

 

Amicus Therapeutics Company used to rely on contract manufacturing alone since they had no capability and adequate resources to stand on their own. It made the company fall into a financial crisis after termination of the collaboration agreement with The Shire in 2009. However, in 2010 Amicus Therapeutics received the grant worth $ 210, 300 from the Alzheimer`s Drug Discovery Foundation. By the end of the year 2015, the Amicus Therapeutics had acquired Scioderm for over $ 947 million in both cash and stock (YahooFinance).

 

The amicus Therapeutics pharmaceutical firm has become a leading business and science driven in delivering meaningful benefits and healthcare to their patients globally. The company`s product pipeline and technology platform put in place positions the qualified and experienced staffs at the forefront of developing therapies to meet significant unmet needs for rare and orphan diseases. The company through research is determined to develop drugs for neurodegenerative diseases including Parkinson`s and Alzheimer`s.

More about Amicus Therapeutics On Crunchbase | Facebook | Twitter

When Enough Is Exactly Enough

– More Money Than You Can Handle

It’s hard to describe how one man can earn in a year more money than hundreds of people will earn in their entire lifetimes. We all desire a more bountiful life and one with more pleasantry and ease. For many, this means having more or extra money to go around. The real question that comes to mind deal with actually having the money you desire. Read more on nytimes.com

But there’s also a real problem that exists when you have more than you can handle. There are responsibilities that often aren’t clear to see prior to becoming rich. That’s why it actually takes a certain type of understanding to both earn and retain wealth. It’s this understanding that we see in George Soros.

For years, this single man has been hailed as one of the wealthiest alive. Today, this still holds true. Mr. Soros’ wealth steadies itself in the billions and year after year.

The Source Of All His Wealth

But you might be wondering where all of this wealth actually came from. And it’s a good question to ask. George would be considered the “God Father” within the investing world. He made his money from riding stocks where he often knew they would go. In fact, he did this so well that he’s also been know for disrupting the economies of nations.

It was even reported once that when President Donald Trump was elected that George Soros took money out of his stocks and helped to start a large decline we saw in the markets. But the exact opposite is also true. Whether Mr. Soros speaks about predictions or puts money into an investment, the entire world is affected. Read this article at Washington Times.

This is simply the power of having more money than you can possibly handle.

A Strategy Never To Be Forgotten

We’ve seen this leverage with Soros only because he happens to be a very smart man.

This is coupled with the fact that George Soros earned a great education that enabled him to soar. He then found the right mentorship in his youth, and each of these things had changed his life. The collective intelligence lets George foresee market conditions that other can’t.

His strategies make him appear to be beyond human and will for many years more to come.

A Look At A Renowned Professional Recruiter, Julie Zuckerberg

The success of any enterprise highly relies on both internal and external factors affecting its operations. External factors cannot be controlled in any way by the business owner, but the positive side is that they affect all businesses in your line of operation not excluding your competitors. Internal factors affect your firm only, and they are subject to control to suit the particular needs of your company. One such factor that is under the control of any business is its recruitment. Hiring qualified staff in all respects is a plus to any organization since it increases its level of productivity compared to one that settles for sub-standard employees. For excellent recruitment, it is advisable to involve the services of a recruiting expert like Julie Zuckerberg.

 

Julie Zuckerberg is a New York-based Executive Recruitment Lead and Talent Acquisition Leader at Deutsche Bank. Like most professionals, she attended her higher education in the City University of New York-Brooklyn College. She pursued Philosophy and then furthered her studies in Law at the New York Law School.

 

After school, Julie Zuckerberg commenced her career by joining Hudson. Here, she served as a Director in charge of candidate placement. For five years, Julie served in the institution where she hired attorneys, case managers, paralegals, support staff and other categories of employees. She offered her unique professional services successfully by providing information about the job, details, and guidelines of their prospects, benefits, and promotion. She served as an excellent bridge between the employees and the management in case of any hitches at work. Besides, she helped resolve these issues within the legal framework and agreement thanks to her rich background in Law. Besides, she exercised her philosophical skills by offering counsel to employees, listening to their grievances, coaching them and also assisting with conflict resolution.

 

About a decade ago, Julie Zuckerberg changed ship to Citi Global Consumer Bank also served in New York as an Executive Recruiter. Her efforts were of great help to the management as she advised on the company’s recruitment strategies and compensation trends that set it apart and gave it a competitive edge over its competitors. Moreover, she helped with the talent development, planning, and enhancement of ideas besides negotiating equity buyouts, claw-backs, immigration, relocation and other issues engulfing recruitment. Also, she handled the expatriate and international relocations for the firm.

 

Due to Julie Zuckerberg’s notable performance and excellent skills, she was on top of the list of becoming the Executive Recruiter for Citi Global Functions. Having served in the company for a considerable length, she gained the necessary exposure and know-how about the recruiting process. Julie was wholly empowered with information, knowledge, and skills since she was also responsible for hiring top-level employees for the organization and its branches.

 

Julie Zuckerberg currently works with Deutsche Bank as its Talent Acquisition Lead. Here, she assists in coaching and offering counsel to the Recruitment Executive Committee. She is also at the helm of the team that hires MD level positions and negotiations. She is a master in recruitment and believes that recruiting the right people is a crucial success driver in any business.

 

Whitney Wolfe is a true Technology Wolf

Born in Salt Lake City Utah, and a resident of Austin, Texas, Mrs. Whitney Wolfe has already made a huge impact in the business world as a young 27-year-old American entrepreneur. Mrs. Whitney Wolfe received her degree in International Studies from Southern Methodist University in Texas. She is the founder and CEO of Bumble, a highly successful location based social and dating application. Bumble facilitates communication between interested people. This technology uses Facebook to build its user profile with photos and basic information, including the user’s educational background and current job. Mrs. Whiteny Wolfe has also previously been aggressively active as the co-founder of the dating app Tinder. Tinder uses GPS location and searching features to allow mutually interested users to engage in chat; it is an app commonly used as a dating service. However, Tinder has branched out to provide lots of other functionality, making it an ideal general-purpose social media application as well.

Incredibly enough, as of April 2016, Tinder and Bumble are the first and fourth most popular dating app on the internet, based on their huge user base. No wonder Mrs. Whitney Wolfe was named as Business Insider’s 30 most important women under 30 years of age, in the technology sector. In 2016, Mrs. Whitney Wolfe was awarded Elle magazine’s “Women in Tech” prize. Wolfe was also presented by Forbes as one of the brightest young entrepreneurs in their 2017 “30 under 30” awards. As early as her college days, Mrs. Whitney Wolfe exhibited great talents and leadership skills. She started her own business at the age of 19, selling bamboo tote bags to benefit areas of the world affected by the BP oil spill. Mrs. Whiteny Wolfe definitely considers herself a feminist rooting fo equality and encouraging women to take active roles.

Watch https://www.youtube.com/watch?v=zrxxBd1UJxg for more.

The OSI Group CEO; Sheldon Lavin Championing Innovative Growth

Sheldon Lavin a tycoon in Illinois and is married to one wife and has three children who are all married. He is the president of OSI International Foods Ltd and also serves as the General Trustee at Rush University Medical Center. Both Mr. Lavin and the company have received awards under his leadership. The Global Visionary Award is meant to honor visionaries of different fields for accomplishing their goals and making their dreams a reality. On 20th February 2017; Lavin received the Global Visionary Award at a ceremony in India and OSI Group also received the Globe of Honor award in 2016 for its environmental management effort.

Sheldon Lavin joined the meat industry over 43 years ago after a successful career in the banking industry. He also owned a financial consulting firm. He has since served as the CEO of OSI Group and has played a significant role in transforming the company from a small bugger supplier to a worldwide supplier of a variety of food products.

OSI Group is a large company that has an average of 20,000 employees annually. The company has a unique and family oriented culture that has been adopted by all the employees. The employees are very important to the company and are respected and as a result, the company experiences very minimal turnover. Lavin considers all employees of OSI Group as part of his extended family.

During the 1970’s there was continuous expansion of OSI Group in Europe and North America and further into Taiwan and South America in the 1980’s. Sheldon Lavin gained 100% ownership of the company as a result of one of the partners selling out and the last one retiring. Overtime, the company expanded into other countries like China, Japan, Philippines, Australia, India, and South Africa.

Today, Lavin’s focus has shifted to growth of the company in Europe and Asia. Lavin is proud of the growth of OSI Group over the last years and of the fact that currently, the company has at least 55 branches in 16 countries across the world, it is evident that OSI Group has a bright future.

Learn more about OSI group: http://www.wattagnet.com/articles/27248-osi-group-buys-former-tyson-foods-plant-in-chicago

Bone Regeneration Treatment Is Being Moved Into The Future By Cameron Clokie

Dr. Cameron Clokie is an oral and maxillofacial surgeon, scientist as well as a serial entrepreneur. He is the CEO of Induce Biologics Inc., which is a company the strives to bring new technologies to musculoskeletal reconstruction. He has over 3 decades of experience under his belt, and has written papers and made numerous presentations, both nationally and internationally on bone reconstruction and regenerative medicine.

In older, more common methods of reconstructive surgery on bone, when a section of bone was needed it was taken from another spot on the patients body that could spare it.

The patient then had to heal for weeks in the hospital, some of that time in ICU. With this new method a putty like gel containing bone morphogenetic protein is shaped to fit the patient’s need and implanted. Read more:  Cameron Clokie DDS, Ph.D.: Executive Profile & Biography

This is a protein that coaxes the body to grow bone to replace the section. At this time a metal rod is used to support the section. This method means less time in surgery and less time spent recovering too. At this time the procedure is expensive because of the cost of bone morphogenetic protein. This method has been used to fuse the spine as well as to regrow the long bone of the limbs.

By the late 1990’s Dr. Cameron Clokie had used bone morphogenetic protein to grow a section of jaw bone. He discovered that it takes a lot of bone to derive the protein, he had to grind the arm and leg bones of 40 cadavers to collect just three milligrams of the protein.

Cameron Clokie wants to come up with a cheaper way to produce the protein so that this is a treatment that can be used for more people.

At this time he plans to place the human gene that produces it into goat embryos. In theory the goats would pruduce large quantities of the protein in their milk. This is similar to the way spider-silk protein for medical and industrial uses was made by injecting it into a goat embryo and then cloning that goat to produce a herd.

Learn more about Cameron Clokie: https://www.dentevents.com/speaker-profile/dr-cameron–clokie/c12024915

Kim Dao Checks Into a Capsule Hotel!

YouTuber and beauty guru Kim Dao’s channel is devoted to makeup, fashion, and documenting her travels around Japan. In her video “CAPSULE HOTEL IN JAPAN EXPERIENCE | Shop in Akihabara” (https://www.youtube.com/watch?v=Xbb4WAHGAVE), Kim Dao shops in Tokyo’s Akihabara area and checks into one of Japan’s infamously claustrophobic capsule hotels. Kim Dao looks over her accommodations at the female-only Akihabara Bay Hotel, and comments that the sleeping capsule is clean and not too small. Separate shower rooms and sink areas are well-stocked with skin- and hair-care products. After storing her bag in the provided locker, Kim Dao heads out with her friend Emma. After a quick lunch, they check out some of the anime stores that Akihabara is known for. Kim and Emma’s first stop is a retro video game store that offers vintage games and consoles. In a nearby anime gift shop, Kim Dao purchases a stuffed Pikachu. After that, it’s off to Don Quijote, a chain store, where Kim Dao picks up a mobile phone cable and some fun Pikachu socks. It’s time for a break and Kim and Emma head to the arcade to play Dance Dance Revolution and try their luck at the claw machine. A Pokemon-themed ice cream sandwich is followed by dinner at McDonald’s. With some difficulty, Kim Dao and Emma devour 50 chicken McNuggets and call it a day. Finally back at the hotel, they make use of the beauty products available and head to their unexpectedly comfortable capsules for some well deserved rest.

 

Secure Used BMW Surveys At Beverly Hills Auto

Buying a used BMW from a dealership like Beverly Hills Auto Group is a big decision. BMW models retain value even when pre-owned, but should be examined in order to save future hassles. After a lengthy research period regarding the type of Beverly Hills Auto Group BMW desired, a buyer should first and foremost insist on an in-person examination. This examination should include surveys of the vehicle’s body and a performance test-run to witness a demonstration of engine integrity. If a used BMW is excluded from these types of examinations, it is a sure indication that the model has a few problems.

 

The Beverly Hills Auto Group in New York only features used BMW models that meet company and consumer expectations. Not only do the representatives of Beverly Hills Auto Group assist buyers in finding used models in excellent condition, but are willing to demonstrate the integrity of the company’s stock in any way that is helpful. This includes engine detailing, car body details, and test drives before purchase.

EOS Lip Balm Overtaking Chapstick

The company Evolution of Smooth, or EOS for short, has overtaken Chapstick as the number two brand of lip balm on the market. Their sales have skyrocketed in recent years, especially since it has been seen popping out of the handbags of multiple celebrities, including the likes of Miley Cyrus, Kim Kardashian, and Christina Aguilera. The product been seen in multiple beauty magazines, and now it seems that all that publicity is starting to pay off, big time.

The company’s cofounder, Sanjiv Mehra, explained in a recent interview in Fast Company about their strategy for building a $250 million company seemingly out of nowhere.

“Not necessarily building up information about it was something quite deliberate on our part,” he said, using the mystery as a marketing strategy.

But that strategy seems to be changing.

“As we’ve grown, we believe that it is important for consumers to know a little bit more about the business we are and the values we stand for.”

One of the big attractions to this lip balm, besides is clever Facebook marketing, is the vast number of flavors and colors available in the EOS lip balm line. Chapstick is known for cherry and plain wax, while EOS has flavors like honeydew melon and grapefruit. Their colorful and clever packaging has really brought them a lot of their success as well, especially once they got displays in nation-wide Walgreens and Target chains in 2010.

http://www.ebay.com/bhp/eos-lip-balm

https://www.amazon.ca/eos-Pomegranate-Raspberry-Lip-Balm/dp/B00B6A9KTU

EOS is also well known for the organic and sustainable nature of their products, something that is very popular with their targeted younger demographic. Their naturally produced products are some of their most popular.

Swiss Startup Factory Continues to Expand with Mike Baur’s Help

Mike Baur from Fribourg in Switzerland, became fascinated with Banking and Financing at a very young age. He eventually used this fascination as his career path. He received his MBA from Rochester University in New York. He went on to receive an Executive MBA from the University of Berne.

 

He spent the first 20 years of his career working in the Swiss Private Banking industry. He was a commercial apprentice, and worked his way up to an executive board member of a Swiss Bank. After the banking collapse of 2007-2008, Baur became disillusioned with banking and after many years, he decided to take his experience in a different direction and started The Swiss Startup Factory (SSUF) with two partners.

 

SSUF is an accelerator program that uses a three-month course to help new entrepreneurs get started with their ideas and products. The firm provides everything the startups need to get a hold of their product and get it to market. They provide office space, mentoring from successful entrepreneurs, financing, networking and product development planning.

 

The organization started a special branch focused on helping woman, called SSUF Female Founder Network. Lea von Bidder is the head of this division. She is co-founder and VP of Marketing at AVA. Mike is dedicated to helping more women become successful business owners.

 

Mike had been a member of the jury for START Summiteer, at startup at University of St. Gallen. In 2016, he led SSUF’s collaboration with CTI Invest, the platform for finding financial support for startups. He eventually became a deputy managing director for the firm.

 

Baur also led SSUF through a partnership with Fintech Fusion. The two independent accelerators joined forces to expand their businesses by combining French speaking parts of Geneva, with German speaking people in Zurich. The joint venture made both companies stronger.

 

Mike currently handles fundraising events at Swiss Startup Factory. He also finds s financing for the entrepreneurs. In his home town and surrounding area, he spends a lot of time mentoring young entrepreneurs and providing financing to some. Baur is married and currently live with his family near Zurich, Switzerland.